NA-Semax Amidate - Spray (24mg)
NA-Semax Amidate - Spray (24mg)
• Lowest price on the market
• Contains 24mg NA-Semax Amidate (1.5mg/ml, 200mcg/spray)
• Estimated 60 days of research supply (Spray Form)
This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
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Description
Summary
N-Acetyl Semax Amidate is a nootropic peptide known for its cognitive enhancing and neuroprotective properties. It's a variant of the original Semax peptide, developed in Russia, which is structurally analogous to the Adrenocorticotropic hormone (ACTH). Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs.
This peptide comes in three typical forms: Original Semax, N-Acetyl Semax (NAS), and N-Acetyl Semax Amidate. The Amidate version is often cited as the best due to its modifications, which include an amidated group. This makes it more potent and longer-lasting than the original and NAS forms.
N-Acetyl Semax Amidate works by upregulating the release of brain-derived neurotrophic factor (BDNF) in the hippocampus. It also increases the levels of tropomyosin receptor kinase B (TrkB), and it also modulates other monoamines as well.
Variants of Semax have also shown potential in improving memory. A small-scale Russian study in healthy males reported that Semax increased memory and attention during "extreme" or "highly-demanding" tasks.
Analysis
Pharmacology
| Other Names | N Acetyl Semax Amidate, NA-Semax, Acetyl-Semax, Acetylsemax, Cemax, семакс, ACTH (4-7), Pro-Gly-Pro-, ACTH (4-7), prolyl-glycyl-proline-, Pro-Gly-Pro-ACTH (4-7), {Ac}-MEHFPGP-NH2 |
| Status | Russian Equivalent Early Phase |
| Pubchem CID | 9811102 (w/o NA+A) |
| CAS Number | 80714-61-0 (w/o NA+A) |
| IUPAC Name | (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid (w/o NA+A) |
| Molecular Formula | C37H51N9O10S |
| Smiles | CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N (w/o NA+A) |
Attributes
| Total Product Weight | 55g |
| Product Form | 12ml ±5% in 20ml Bottle (0.1ml per spray ±10%) NOTE: Labels may be innacurate, white tops are 12mL, not 16mL |
| Physical Form | Liquid, solved in deionized water (98.8%), stabilized with Polysorbate 80 (1%) and sterilized with sodium benzoate (0.2%) |
| Bottle Dimensions | 30x120mm |
| $/g (Cost Per Gram) | 1125$ |
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